Dimitri P S, Wall C, Rauch S D
Harvard University-Massachusetts Institute of Technology Division of Health Sciences and Technology, Boston, MA, USA.
J Vestib Res. 2001;11(6):405-12.
This paper discusses the use of vestibular testing to discriminate between right (n = 29) and left (n = 27) Ménière's disease. We examined reduced vestibular response (RVR), directional preponderance, and spontaneous and positional nystagmus measurements from electronystagmography, as well as the asymmetry measurements from the sinusoidal harmonic acceleration test, to determine whether multivariate logistic regression could improve upon the discrimination performance of RVR alone. We found that patients with a spontaneous or positional nystagmus often had a "recovery nystagmus", beating in the opposite direction of that predicted for an acute lesion. When present, the direction and magnitude of such nystagmus could be used in the classification algorithm to increase the discriminatory power over RVR alone, but in these patients the rotation test asymmetry measurements were rendered useless. In the absence of spontaneous or positional nystagmus, asymmetry measurements significantly enhanced right/left discrimination. Directional preponderance was insignificant in determining the side of lesion.
本文讨论了使用前庭测试来区分右侧梅尼埃病（n = 29）和左侧梅尼埃病（n = 27）。我们检查了眼震电图的前庭反应降低（RVR）、优势偏向、自发性和位置性眼球震颤测量值，以及正弦谐波加速度测试的不对称测量值，以确定多变量逻辑回归是否能比单独使用RVR的判别性能有所提高。我们发现，有自发性或位置性眼球震颤的患者通常会出现“恢复性眼球震颤”，其跳动方向与急性病变预测的方向相反。当出现这种眼球震颤时，其方向和幅度可用于分类算法中，以提高相对于单独使用RVR的判别能力，但在这些患者中，旋转测试不对称测量值变得无用。在没有自发性或位置性眼球震颤的情况下，不对称测量值显著增强了右侧/左侧的区分。优势偏向在确定病变侧方面无显著意义。
