Kowalczyk Jamease, Jolly Pauline, Karita Etienne, Nibarere Joseph-Ardent, Vyankandondera Joseph, Salihu Hamisu
Department of Epidemiology and International Health, University of Alabama at Birmingham, 35294, USA.
J Acquir Immune Defic Syndr. 2002 Dec 1;31(4):408-15. doi: 10.1097/00126334-200212010-00007.
This study investigated factors related to acceptability of voluntary counseling and testing (VCT) for HIV among pregnant women presenting in labor in Kigali, Rwanda, in an era of free and effective antiretroviral drugs for prevention of perinatal transmission of HIV. A pilot-tested questionnaire was administered to study participants to solicit information regarding their intentions to accept or refuse VCT and treatment of HIV infection during labor and delivery if confirmed infected. Two factors correlated significantly with the acceptance rate. The strongest predictive factor for acceptability of HIV testing was the profession of the male partner. Women whose partners had skilled and well-paid jobs were about four times more likely to accept HIV testing than were women whose partners were unemployed (adjusted odds ratio, 3.5; confidence interval, 1.16-10.85). The other factor significantly associated with the acceptance rate was maternal age. The likelihood of acceptance of HIV testing was about three times higher among women 35 years or older than among younger mothers (adjusted odds ratio, 3.1; confidence interval, 1.01-9.4). For every 5-year increment in maternal age, the odds of acceptance of HIV testing increased by a factor of 1.20. Using this important finding, we constructed an acceptance rate probability curve that could serve as a useful tool to evaluate the efficacy of future interventions aimed at improving the acceptability rate of HIV testing among pregnant women at the study site.
在卢旺达基加利,处于免费且有效的抗逆转录病毒药物可预防艾滋病毒围产期传播的时代,本研究调查了在分娩时就诊的孕妇中与自愿咨询和检测(VCT)可接受性相关的因素。向研究参与者发放了经过预测试的问卷,以获取有关她们在分娩期间如果被确诊感染艾滋病毒,接受或拒绝VCT及艾滋病毒感染治疗的意向信息。有两个因素与接受率显著相关。艾滋病毒检测可接受性的最强预测因素是男性伴侣的职业。伴侣有技能且收入高的女性接受艾滋病毒检测的可能性比伴侣失业的女性高出约四倍(调整后的优势比为3.5;置信区间为1.16 - 10.85)。另一个与接受率显著相关的因素是产妇年龄。35岁及以上的女性接受艾滋病毒检测的可能性比年轻母亲高出约三倍(调整后的优势比为3.1;置信区间为1.01 - 9.4)。产妇年龄每增加5岁,接受艾滋病毒检测的几率就增加1.20倍。利用这一重要发现,我们构建了一个接受率概率曲线,该曲线可作为一种有用的工具,用于评估未来旨在提高研究地点孕妇艾滋病毒检测接受率的干预措施的效果。