Alapont Alacreu J M, Montaner Ramírez M J, Pontones Moreno J L, Valls Blasco F, Vera-Sempere F J, Jiménez-Cruz J F
Servicio de Urología, Hospital Universitario La Fe, Valencia.
Actas Urol Esp. 2002 Sep;26(8):585-8. doi: 10.1016/s0210-4806(02)72833-7.
Pure small cell carcinoma of the prostate is rare (less than 1% of all prostatic neoplasm). As a result there are few reports in the literature that describe the salient features and appropriate management of this cancer (less than 200 cases reported). Small cell carcinomas of the prostate are a heterogeneous group of tumors, a number of them have neuroendocrine differentiation and are highly aggressive, commonly with visceral metastases at time of diagnosis. Complete temporary remission has been reported with chemotherapy but this tumor has a poor prognosis. The median overall survival from the time of diagnosis is between 5-17.5 months. We report 2 new cases of small cell carcinoma of the prostate and a review of the literature.
前列腺纯小细胞癌很罕见（占所有前列腺肿瘤的比例不到1%）。因此，文献中很少有报道描述这种癌症的显著特征和恰当治疗方法（报道的病例不到200例）。前列腺小细胞癌是一组异质性肿瘤，其中一些具有神经内分泌分化，侵袭性很强，通常在诊断时就已出现内脏转移。化疗后曾有完全缓解的报道，但这种肿瘤预后较差。从诊断时起计算的中位总生存期在5至17.5个月之间。我们报告2例新的前列腺小细胞癌病例并对文献进行综述。
