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[纵隔镜检查在非小细胞肺癌中是必要的术前检查吗?]

[Is mediastinoscopy a necessary preoperative procedure in non-small cell lung cancer?].

作者信息

Heitmann Ellinor Pay, Alexandersen Olaf, Moland Jarl

机构信息

Medisinsk avdeling, lungeseksjonen, Nordland sentralsykehus 8092 Bodø.

出版信息

Tidsskr Nor Laegeforen. 2002 Sep 30;122(23):2268-9.

PMID:12448265
Abstract

BACKGROUND AND METHODS

Over the decade 1990 to 2000, our hospital performed 149 mediastinoscopies in order to support CT scans in the staging on mediastinal lymph nodes in non-small cell lung cancer.

RESULTS

CT scans indicated N0-N1 tumours in 64 patients; mediastinoscopy showed that eight of these had N2 disease. Another seven N2 tumours were found in the postoperative histological diagnosis. N2 tumours were indicated by CT scans in 79 patients. Mediastinoscopy proved 53 of these to be N0-N1 tumours; 46 cases were operated, 33 proved to be N0-N1. N3 tumours were indicated by CT scans in six patients. Mediastinoscopy proved this wrong in establishing that three had N0, which was confirmed in the postoperative findings.

INTERPRETATION

Only one serious bleeding occurred in a total of 193 mediastinoscopies over the ten-year period. No other complications were reported, hence our material shows that mediastinoscopy is a fairly safe procedure. It is a necessary diagnostic supplement when N2 and N3 tumours are found by CT scan. The benefit of mediastinoscopy is more uncertain when the CT findings are N0-N1 tumours.

摘要

背景与方法

在1990年至2000年的十年间,我院进行了149例纵隔镜检查,以辅助非小细胞肺癌纵隔淋巴结分期的CT扫描。

结果

CT扫描显示64例患者为N0-N1期肿瘤;纵隔镜检查显示其中8例为N2期疾病。术后组织学诊断又发现7例N2期肿瘤。CT扫描显示79例为N2期肿瘤。纵隔镜检查证实其中53例为N0-N1期肿瘤;46例接受手术,33例被证实为N0-N1期。CT扫描显示6例为N3期肿瘤。纵隔镜检查证实其中3例诊断错误,术后结果证实其为N0期。

解读

在这十年间的193例纵隔镜检查中,仅发生1例严重出血。未报告其他并发症,因此我们的资料表明纵隔镜检查是一种相当安全的操作。当CT扫描发现N2和N3期肿瘤时,纵隔镜检查是必要的诊断补充。当CT检查结果为N0-N1期肿瘤时,纵隔镜检查的益处更不确定。

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