基于核磁共振的干酪乳杆菌二氢叶酸还原酶与甲氧苄啶和烟酰胺腺嘌呤二核苷酸磷酸复合物的溶液结构 - Suppr

Suppr

超能文献

NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH.

作者信息

Polshakov Vladimir I, Smirnov Eugeni G, Birdsall Berry, Kelly Geoff, Feeney James

出版信息

J Biomol NMR. 2002 Sep;24(1):67-70. doi: 10.1023/a:1020659713373.

DOI:10.1023/a:1020659713373

PMID:12449420

Abstract

摘要

相似文献

NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH.

J Biomol NMR. 2002 Sep;24(1):67-70. doi: 10.1023/a:1020659713373.

NMR structures of apo L. casei dihydrofolate reductase and its complexes with trimethoprim and NADPH: contributions to positive cooperative binding from ligand-induced refolding, conformational changes, and interligand hydrophobic interactions.

Biochemistry. 2011 May 10;50(18):3609-20. doi: 10.1021/bi200067t. Epub 2011 Apr 14.

Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH.

J Biomol NMR. 2005 Sep;33(1):69-72. doi: 10.1007/s10858-005-1475-z.

Crystallographic investigation of the cooperative interaction between trimethoprim, reduced cofactor and dihydrofolate reductase.

FEBS Lett. 1986 Apr 7;199(1):61-7. doi: 10.1016/0014-5793(86)81224-8.

Multinuclear NMR characterization of two coexisting conformational states of the Lactobacillus casei dihydrofolate reductase-trimethoprim-NADP+ complex.

Biochemistry. 1984 Sep 25;23(20):4733-42. doi: 10.1021/bi00315a032.

Characterization of rates of ring-flipping in trimethoprim in its ternary complexes with Lactobacillus casei dihydrofolate reductase and coenzyme analogues.

Biochemistry. 1999 Nov 30;38(48):15962-9. doi: 10.1021/bi9915263.

Hydrogen bonding effects on 31P NMR shielding in the pyrophosphate group of NADPH bound to L. casei dihydrofolate reductase.

FEBS Lett. 1991 Oct 7;291(1):21-3. doi: 10.1016/0014-5793(91)81094-o.

Solution structure of bound trimethoprim in its complex with Lactobacillus casei dihydrofolate reductase.

Biochemistry. 1994 Oct 18;33(41):12416-26. doi: 10.1021/bi00207a008.

Trimethoprim binding to Lactobacillus casei dihydrofolate reductase: a 13C NMR study using selectively 13C-enriched trimethoprim.

Biochemistry. 1986 Apr 22;25(8):1925-31. doi: 10.1021/bi00356a014.

31P NMR studies of NADPH and NADP+ binding to L. casei dihydrofolate reductase.

Nature. 1975 Oct 16;257(5527):564-6. doi: 10.1038/257564a0.

引用本文的文献

Systematic identification of trimethoprim metabolites in lettuce.

Anal Bioanal Chem. 2022 Apr;414(9):3121-3135. doi: 10.1007/s00216-022-03943-6. Epub 2022 Feb 9.

Distal Regions Regulate Dihydrofolate Reductase-Ligand Interactions.

Methods Mol Biol. 2021;2253:185-219. doi: 10.1007/978-1-0716-1154-8_12.

A fluorogenic TMP-tag for high signal-to-background intracellular live cell imaging.

ACS Chem Biol. 2013 Aug 16;8(8):1704-12. doi: 10.1021/cb300657r. Epub 2013 Jun 19.

Second-generation covalent TMP-tag for live cell imaging.

J Am Chem Soc. 2012 Aug 22;134(33):13692-9. doi: 10.1021/ja303374p. Epub 2012 Aug 9.

Biochemistry. 2011 May 10;50(18):3609-20. doi: 10.1021/bi200067t. Epub 2011 Apr 14.

An in vivo covalent TMP-tag based on proximity-induced reactivity.

ACS Chem Biol. 2009 Jul 17;4(7):547-56. doi: 10.1021/cb900062k.

The solution structure of Bacillus anthracis dihydrofolate reductase yields insight into the analysis of structure-activity relationships for novel inhibitors.

Biochemistry. 2009 May 19;48(19):4100-8. doi: 10.1021/bi802319w.

Dynamic dysfunction in dihydrofolate reductase results from antifolate drug binding: modulation of dynamics within a structural state.

Structure. 2009 Mar 11;17(3):386-94. doi: 10.1016/j.str.2009.01.005.

In pursuit of virtual lead optimization: pruning ensembles of receptor structures for increased efficiency and accuracy during docking.

Proteins. 2009 Apr;75(1):62-74. doi: 10.1002/prot.22214.

In pursuit of virtual lead optimization: the role of the receptor structure and ensembles in accurate docking.

Proteins. 2008 Nov 15;73(3):566-80. doi: 10.1002/prot.22081.

本文引用的文献

Characterization of rates of ring-flipping in trimethoprim in its ternary complexes with Lactobacillus casei dihydrofolate reductase and coenzyme analogues.

Biochemistry. 1999 Nov 30;38(48):15962-9. doi: 10.1021/bi9915263.

Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs.

J Mol Biol. 2000 Jan 14;295(2):307-23. doi: 10.1006/jmbi.1999.3328.

Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate.

Protein Sci. 1999 Mar;8(3):467-81. doi: 10.1110/ps.8.3.467.

Crystallography & NMR system: A new software suite for macromolecular structure determination.

Acta Crystallogr D Biol Crystallogr. 1998 Sep 1;54(Pt 5):905-21. doi: 10.1107/s0907444998003254.

The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate.

J Mol Biol. 1998 Mar 20;277(1):119-34. doi: 10.1006/jmbi.1997.1560.

Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.

Biochemistry. 1997 Jan 21;36(3):586-603. doi: 10.1021/bi962337c.

NMR detection of arginine-ligand interactions in complexes of Lactobacillus casei dihydrofolate reductase.

Eur J Biochem. 1996 Jun 1;238(2):435-9. doi: 10.1111/j.1432-1033.1996.0435z.x.

Preliminary crystallographic data for Pneumocystis carinii dihydrofolate reductase.

J Mol Biol. 1993 Mar 20;230(2):679-80. doi: 10.1006/jmbi.1993.1183.

Basis of selectivity of antibacterial diaminopyrimidines.

J Chemother. 1993 Dec;5(6):393-9.

Solution structure of bound trimethoprim in its complex with Lactobacillus casei dihydrofolate reductase.

Biochemistry. 1994 Oct 18;33(41):12416-26. doi: 10.1021/bi00207a008.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验