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[大鼠母亲优势半球或非优势半球感觉运动皮层的单侧损伤及其后代在“旷场”中的情绪行为]

[Unilateral injury of sensorimotor cortex of the dominant or subdominant hemispheres of rats-mothers and emotional behavior of their offsprings in the "open field"].

作者信息

Avaliani T V, Seriakova O R, Czabak-Garbacz R, Shabaev V V

机构信息

Institute for Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg.

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 2002 Sep-Oct;52(5):618-25.

Abstract

Neurohumoral disorders in mothers caused by brain injury, infection, hypoxia, and other pathological factors result in motor and psychoemotional disorders in children. Emotional behavior of 30-day-old offsprings of female rats with unilateral sensorimotor brain injury was studied in the "open field". Individual behavior was estimated (the probability of certain acts and significant transfers between them). Behavioral disorders in rat offsprings depended on the side (left of right) of mother's brain injury and "handedness". The right-side mother's injury turned to be more deleterious. Behavioral alterations were stronger in offsprings of ambidextral and left-handed females than in those born by right-handed males with the same sensorimotor injury.

摘要

由脑损伤、感染、缺氧及其他病理因素引起的母亲神经体液紊乱会导致儿童出现运动和心理情绪障碍。在“旷场”实验中研究了单侧感觉运动脑损伤雌性大鼠30日龄后代的情绪行为。评估了个体行为(特定行为的概率及其之间的显著转换)。大鼠后代的行为障碍取决于母亲脑损伤的侧别(左侧或右侧)以及“用手习惯”。右侧母亲脑损伤的危害更大。与具有相同感觉运动损伤的右利手雄性大鼠所生后代相比,双手并用和左利手雌性大鼠的后代行为改变更明显。

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