Barbagallo Giuseppe M V, Lanzafame Salvatore, Nicol etti Giovanni F, Platania Nunzio, Albanese Vincenzo
Institutes of Neurosurgery and Pathological Anatomy, University of Catania, Catania, Italy.
J Neurosurg. 2002 Mar;96(2 Suppl):230-5. doi: 10.3171/spi.2002.96.2.0230.
The authors report an exceedingly rare case of a patient harboring a primary, spinal, C1-2, intradural, extramedullary meningeal sarcoma in which there were glial fibrillary acidic protein-immunoreactive components, but, importantly, no physical connection with neural tissue. On initial diagnostic imaging, neuroradiological features suggestive of a spinal meningioma were demonstrated in this 73-year-old man. He underwent a C1-2 laminectomy and removal of the posterior ring of the foramen magnum, and the lesion was excised. Histological and immunohistochemical testing showed a gliosarcoma. The clinical, radiological, and operative data are reviewed, as are the histopathological findings. To the authors' knowledge, this is the first case of a primary spinal intradural extramedullary gliosarcoma reported in the literature.
