Valença Alexandre M, Nardi Antonio E, Nascimento Isabella, Zin Walter A, Lopes Fabiana L, Mezzasalma Marco A, Versiani Marcio
Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro-RJ, Brazil.
Psychiatry Res. 2002 Nov 15;112(3):269-72. doi: 10.1016/s0165-1781(02)00222-6.
We examined whether responses to the carbon dioxide (CO(2)) challenge test were correlated with clinical response. Thirty-four panic disorder patients participated in a CO(2) test after 1 h, 2 weeks and 6 weeks of treatment with clonazepam (2 mg/day) or placebo. The clonazepam group had significantly fewer panic attacks in response to the CO(2) test and the test may predict clinical response.
我们研究了对二氧化碳（CO₂）激发试验的反应是否与临床反应相关。34名惊恐障碍患者在接受氯硝西泮（2毫克/天）或安慰剂治疗1小时、2周和6周后参加了CO₂试验。氯硝西泮组对CO₂试验的惊恐发作明显减少，该试验可能预测临床反应。
