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脑脊液吸收部位之谜:新线索

The puzzle of where cerebrospinal fluid is absorbed: new pieces.

作者信息

Maurizi C P

机构信息

Department of Pathology, Houston Medical Center, GA 31093, USA.

出版信息

Med Hypotheses. 2003 Jan;60(1):102-3. doi: 10.1016/s0306-9877(02)00340-7.

DOI:10.1016/s0306-9877(02)00340-7
PMID:12450773
Abstract

The widely held theory of cerebrospinal fluid (CSF) absorption by the arachnoid villus system cannot explain the movement of substances within the fluid, the deposition pattern of corpora amylacea on the surface of the brain, and pathological findings in neurological disorders. Experiments studying the movement of melatonin and inulin in the CSF compartment demonstrate that some CSF recycles into the ventricular system and CSF contacting tissue diffusely absorbs some. Photomicrographs of a suprapineal recess portal into the third ventricle are presented. A cycling theory of CSF assigns function to the structure of the choroid fissures and the suprapineal recess.

摘要

关于蛛网膜绒毛系统吸收脑脊液(CSF)的广泛理论无法解释脑脊液中物质的移动、脑表面淀粉样体的沉积模式以及神经疾病中的病理发现。研究褪黑素和菊粉在脑脊液腔室中移动的实验表明,一些脑脊液会循环回脑室系统,并且与脑脊液接触的组织会分散吸收一些。本文展示了松果体上隐窝通向第三脑室的显微照片。脑脊液循环理论赋予了脉络膜裂和松果体上隐窝结构相应功能。

相似文献

1
The puzzle of where cerebrospinal fluid is absorbed: new pieces.脑脊液吸收部位之谜:新线索
Med Hypotheses. 2003 Jan;60(1):102-3. doi: 10.1016/s0306-9877(02)00340-7.
2
Choroid plexus portals and a deficiency of melatonin can explain the neuropathology of Alzheimer's disease.脉络丛门和褪黑素缺乏可以解释阿尔茨海默病的神经病理学。
Med Hypotheses. 2010 Jun;74(6):1059-66. doi: 10.1016/j.mehy.2009.12.026. Epub 2010 Jan 13.
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Melatonin enters the cerebrospinal fluid through the pineal recess.褪黑素通过松果体隐窝进入脑脊液。
Endocrinology. 2002 Jan;143(1):84-90. doi: 10.1210/endo.143.1.8585.
4
Recirculation of cerebrospinal fluid through the tela choroidae is why high levels of melatonin can be found in the lateral ventricles.
Med Hypotheses. 1991 Jun;35(2):154-8. doi: 10.1016/0306-9877(91)90041-v.
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Pinealocytes contacting the cerebrospinal fluid of the suprapineal recess in the Mongolian gerbil (Meriones unguiculatus).与蒙古沙鼠(长爪沙鼠)松果体上隐窝脑脊液接触的松果体细胞。
Cell Tissue Res. 1982;222(1):177-85. doi: 10.1007/BF00218298.
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High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus.第三脑室脑脊液中高浓度褪黑素并非由于盖伦静脉血经脉络丛再循环所致。
Endocrinology. 1999 Oct;140(10):4399-405. doi: 10.1210/endo.140.10.7074.
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Cardiotrophin-1 in choroid plexus and the cerebrospinal fluid circulatory system.脉络丛和脑脊液循环系统中的心肌营养素-1
Neuroscience. 2004;127(1):43-52. doi: 10.1016/j.neuroscience.2004.03.065.
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A cycle of cerebrospinal fluid: supporting evidence and theoretical considerations.脑脊液循环:支持证据与理论思考
Med Hypotheses. 2000 Mar;54(3):417-22. doi: 10.1054/mehy.1999.0863.
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A liquor contacting area in the pineal recess of the golden hamster (Mesocricetus auratus).金黄仓鼠(Mesocricetus auratus)松果体隐窝中的脑脊液接触区。
Anat Embryol (Berl). 1978 Jun 12;153(3):295-304. doi: 10.1007/BF00315932.
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CSF generation by pineal gland results in a robust melatonin circadian rhythm in the third ventricle as an unique light/dark signal.松果体产生的脑脊液在第三脑室形成强大的褪黑素昼夜节律,作为一种独特的明暗信号。
Med Hypotheses. 2016 Jan;86:3-9. doi: 10.1016/j.mehy.2015.11.018. Epub 2015 Nov 26.

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1
Water and solute secretion by the choroid plexus.脉络丛的水和溶质分泌
Pflugers Arch. 2007 Apr;454(1):1-18. doi: 10.1007/s00424-006-0170-6. Epub 2006 Nov 21.