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需要肾脏移植的活体肾脏捐赠者:器官获取与移植网络的一份报告。

Living kidney donors in need of kidney transplants: a report from the organ procurement and transplantation network.

作者信息

Ellison Mary D, McBride Maureen A, Taranto Sarah E, Delmonico Francis L, Kauffman H Myron

机构信息

United Network for Organ Sharing, Richmond, VA 23225, USA.

出版信息

Transplantation. 2002 Nov 15;74(9):1349-51. doi: 10.1097/00007890-200211150-00025.

Abstract

BACKGROUND

Our aim was to use the Organ Procurement and Transplantation Network (OPTN) database to determine the number of renal waitlist candidates who previously had been living donors.

METHODS

All living renal donors in the OPTN database were cross-checked against the renal waitlist history files. Additionally, renal transplant programs were contacted that had listed candidates as qualified for four additional allocation points available to patients who previously had donated an organ. Confirmatory phone calls to transplant programs yielded additional cases previously unreported to the United Network for Organ Sharing.

RESULTS

A total of 56 previous living donors were identified as having been subsequently listed for cadaveric kidney transplantation. Forty-three have received transplants; 36 currently have functioning grafts. One died after transplantation. Two candidates died while waiting.

CONCLUSIONS

Living renal donation has long-term risks that may not be apparent in the short term. The numbers here reported underestimate the actual number of living donors with renal failure, because they include only patients listed for a kidney transplant. To determine risk factors for postdonation renal failure, long-term living-donor follow-up data are needed.

摘要

背景

我们的目的是利用器官获取与移植网络(OPTN)数据库来确定既往曾为活体供者的肾移植等待名单候选人数量。

方法

将OPTN数据库中的所有活体肾供者与肾移植等待名单历史档案进行交叉核对。此外,还联系了肾移植项目,这些项目将符合条件的候选人列为可获得额外四个分配积分的对象,这些积分提供给既往曾捐献过器官的患者。对移植项目进行确认性电话随访发现了一些此前未向器官共享联合网络报告的病例。

结果

共识别出56名既往活体供者随后被列入尸体肾移植等待名单。43人已接受移植;36人目前移植肾有功能。1人移植后死亡。2名候选人在等待过程中死亡。

结论

活体肾捐献存在长期风险,短期内可能并不明显。此处报告的数字低估了肾衰竭活体供者的实际数量,因为这些数字仅包括列入肾移植等待名单的患者。要确定捐献后肾衰竭的危险因素,需要长期的活体供者随访数据。

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