Geisthövel W, von zur Mühlen A
Dtsch Med Wochenschr. 1976 Jan 9;101(2):37-42. doi: 10.1055/s-0028-1104030.
Testosterone-binding capacity (TeBG), free-plasma testosterone fraction (%FT), and free-plasma testosterone concentration (AFT) were measured in 24 men with primary and 14 with secondary hypogonadism of various causes, as well as in eight with coital impotence. There was a highly significant correlation between TeBG and %FT (r = minus 0.891; P less than 0.0005). TeBG and %FT did not generally differ from normal in primary hypogonadism, while AFT was normal or decreased, depending on the corresponding whole testosterone concentrations. In secondary hypogonadism there was always an increased TeBG and decreased %FT. Depending on whole testosterone concentration, AFT was low or very low. In impotent subjects TeBG, %FT and AFT were generally normal. The role of AFT determination in andrological diagnosis is discussed.
对24名原发性性腺功能减退和14名各种原因所致继发性性腺功能减退的男性以及8名性交性阳痿患者进行了睾酮结合能力（TeBG）、游离血浆睾酮比例（%FT）和游离血浆睾酮浓度（AFT）的测定。TeBG与%FT之间存在高度显著的相关性（r = -0.891；P < 0.0005）。在原发性性腺功能减退中，TeBG和%FT一般与正常情况无异，而AFT则正常或降低，这取决于相应的总睾酮浓度。在继发性性腺功能减退中，TeBG总是升高而%FT降低。根据总睾酮浓度，AFT较低或非常低。对阳痿患者而言，TeBG、%FT和AFT一般正常。文中讨论了AFT测定在男科诊断中的作用。
