Prieto Alejandro R, Przybysz Aaron, Fischell Tim A
Department of Medicine, Division of Cardiology, Michigan State University, Lansing, Michigan, USA.
Catheter Cardiovasc Interv. 2002 Dec;57(4):437-43. doi: 10.1002/ccd.10370.
The objective of this study was to evaluate the efficacy of treating long coronary lesions (> 30 mm) with either a 40 or a 60 mm long Scimed Cobra balloon followed by focal (contingency) stenting of areas with suboptimal results. Diffuse lesion length is a morphological characteristic associated with a poorer clinical outcome after balloon angioplasty with or without stenting. Patients were enrolled in a prospective randomized fashion to have initial PTCA with either a 40 or a 60 mm long balloon followed by focal stenting in areas with suboptimal results. The MACE rate at 6-month follow-up was collected from all patients and was the primary endpoint of the study. A total of 41 patients were enrolled into the study. The acute procedural success rate was 97.5% with a 6-month MACE rate of 9.8%. The use of long balloons with contingency stenting is a highly effective strategy for the treatment of diffuse coronary lesions.
本研究的目的是评估使用40毫米或60毫米长的Scimed Cobra球囊治疗长冠状动脉病变（>30毫米），随后对效果欠佳区域进行局部（应急）支架置入术的疗效。弥漫性病变长度是一种形态学特征，与无论有无支架置入的球囊血管成形术后较差的临床结局相关。患者以前瞻性随机方式入组，先使用40毫米或60毫米长的球囊进行初始经皮冠状动脉腔内血管成形术（PTCA），随后对效果欠佳区域进行局部支架置入术。收集所有患者6个月随访时的主要不良心血管事件（MACE）发生率，其为该研究的主要终点。共有41例患者纳入该研究。急性手术成功率为97.5%，6个月MACE发生率为9.8%。使用长球囊并进行应急支架置入术是治疗弥漫性冠状动脉病变的一种高效策略。
