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我们如何治疗喘息的婴儿?证据还是轶事。

How do we treat wheezing infants? Evidence or anecdote.

作者信息

Chavasse R J, Bastian-Lee Y, Seddon P

机构信息

The Royal Alexandra Hospital for Sick Children, Brighton BN1 3JN, UK.

出版信息

Arch Dis Child. 2002 Dec;87(6):546-7. doi: 10.1136/adc.87.6.546.

DOI:10.1136/adc.87.6.546
PMID:12456565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1755817/
Abstract

Consultant paediatricians were questioned about their management of wheezing disorders in infants. Salbutamol was the preferred bronchodilator for recurrent wheeze, whereas ipratropium was preferred in viral bronchiolitis. Doses of both medications varied widely. Both inhaled and oral corticosteroids were considered by most respondents. Practice does not clearly follow guidelines or evidence and presumably continues to be based on anecdote.

摘要

儿科顾问医生被问及他们对婴儿喘息性疾病的治疗方法。沙丁胺醇是治疗复发性喘息的首选支气管扩张剂,而异丙托溴铵则是病毒性支气管炎的首选药物。两种药物的剂量差异很大。大多数受访者都考虑使用吸入性和口服皮质类固醇。实际操作并未严格遵循指南或证据,大概仍然是基于经验。

相似文献

1
How do we treat wheezing infants? Evidence or anecdote.我们如何治疗喘息的婴儿?证据还是轶事。
Arch Dis Child. 2002 Dec;87(6):546-7. doi: 10.1136/adc.87.6.546.
2
Bronchodilators and steroids should not be given in viral bronchiolitis - CON.在病毒性细支气管炎中不应给予支气管扩张剂和类固醇——反对意见。
Paediatr Respir Rev. 2019 Nov;32:20-22. doi: 10.1016/j.prrv.2019.09.001. Epub 2019 Oct 8.
3
Bronchodilators and steroids should not be given in viral bronchiolitis - PRO.在病毒性细支气管炎中不应使用支气管扩张剂和类固醇——专业意见。
Paediatr Respir Rev. 2019 Nov;32:18-19. doi: 10.1016/j.prrv.2019.09.002. Epub 2019 Oct 8.
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No effect of cromoglycate treatment in hospitalized infants with respiratory syncytial virus bronchiolitis.
Pediatr Pulmonol. 2003 Nov;36(5):455. doi: 10.1002/ppul.10354.
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No effect of cromoglycate treatment in hospitalized infants with respiratory syncytial virus bronchiolitis.色甘酸治疗对住院呼吸道合胞病毒细支气管炎婴儿无效果。
Pediatr Pulmonol. 2003 Aug;36(2):170. doi: 10.1002/ppul.10334.
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Finnish guidelines for the treatment of laryngitis, wheezing bronchitis and bronchiolitis in children.芬兰儿童喉炎、喘息性支气管炎和细支气管炎治疗指南。
Acta Paediatr. 2016 Jan;105(1):44-9. doi: 10.1111/apa.13162. Epub 2015 Nov 6.
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Efficacy of salbutamol and ipratropium bromide in the management of acute bronchiolitis--a clinical trial.沙丁胺醇与异丙托溴铵治疗急性细支气管炎的疗效——一项临床试验
Respiration. 2008;76(3):283-7. doi: 10.1159/000111817. Epub 2007 Nov 28.
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Efficacy of nebulized ipratropium bromide versus salbutamol in infants with acute bronchiolities.
Bangladesh Med Res Counc Bull. 2008 Dec;34(3):112. doi: 10.3329/bmrcb.v34i3.1861.
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Do bronchodilators have an effect on bronchiolitis?支气管扩张剂对细支气管炎有作用吗?
Crit Care. 2002 Apr;6(2):111-2. doi: 10.1186/cc1466. Epub 2002 Mar 11.
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For which infants with viral bronchiolitis could it be deemed appropriate to use albuterol, at least on a therapeutic trial basis?对于哪些病毒性细支气管炎婴儿,可以考虑使用沙丁胺醇(至少进行治疗性试验)?
Allergol Immunopathol (Madr). 2021 Jan 2;49(1):153-158. doi: 10.15586/aei.v49i1.12. eCollection 2021.

引用本文的文献

1
Impact of a bronchiolitis clinical care pathway on treatment and hospital stay.毛细支气管炎临床护理路径对治疗和住院时间的影响。
Eur J Pediatr. 2012 May;171(5):827-32. doi: 10.1007/s00431-011-1653-9. Epub 2011 Dec 23.

本文引用的文献

1
Persistent wheezing in infants with an atopic tendency responds to inhaled fluticasone.有特应性倾向的婴儿持续性喘息对吸入氟替卡松有反应。
Arch Dis Child. 2001 Aug;85(2):143-8. doi: 10.1136/adc.85.2.143.
2
Randomized trial of salbutamol via metered-dose inhaler with spacer versus nebulizer for acute wheezing in children less than 2 years of age.使用定量吸入器加储雾罐与雾化器吸入沙丁胺醇治疗2岁以下儿童急性喘息的随机试验。
Pediatr Pulmonol. 2000 Apr;29(4):264-9. doi: 10.1002/(sici)1099-0496(200004)29:4<264::aid-ppul5>3.0.co;2-s.
3
Treatment of respiratory syncytial virus bronchiolitis: 1995 poll of members of the European Society for Paediatric Infectious Diseases.呼吸道合胞病毒细支气管炎的治疗:1995年欧洲儿科传染病学会成员民意调查
Pediatr Infect Dis J. 1997 May;16(5):479-81. doi: 10.1097/00006454-199705000-00004.
4
Treatment of recurrent acute wheezing episodes in infancy with oral salbutamol and prednisolone.口服沙丁胺醇和泼尼松龙治疗婴儿期复发性急性喘息发作
Eur J Pediatr. 1996 Jun;155(6):512-6. doi: 10.1007/BF01955192.
5
Nebulised therapy in acute severe bronchiolitis in infancy.婴儿期急性重症细支气管炎的雾化治疗
Arch Dis Child. 1983 Apr;58(4):279-82. doi: 10.1136/adc.58.4.279.