Russell M O, Goldberg H I, Reis L, Friedman S, Slater R, Reivich M, Schwartz E
J Pediatr. 1976 Mar;88(3):382-7. doi: 10.1016/s0022-3476(76)80251-x.
Cerebral angiograms were performed in patients with sickle cell disease and symptoms of stroke to evaluate transfusion therapy for cerebrovascular accidents. Three patients who were transfused repeatedly for one year to maintain less than 30% hemoglobin S were compared to two patients who were not transfused. All patients had abnormal angiograms initially. After one year the angiographic abnormalities resolved in two and improved in one transfused child. The two children who were not transfused showed progressive vascular disease. For all arteriograms, the patients were prepared by transfusion with normal red cells and careful hydration.
对患有镰状细胞病且有中风症状的患者进行脑血管造影，以评估针对脑血管意外的输血治疗效果。将三名接受了一年反复输血以维持血红蛋白S低于30%的患者与两名未接受输血的患者进行比较。所有患者最初的血管造影均异常。一年后，两名接受输血的儿童血管造影异常消失，一名有所改善。两名未接受输血的儿童则显示出进行性血管疾病。对于所有血管造影检查，患者均通过输注正常红细胞并仔细补液来进行准备。
