Bono Aldo, Bartoli Cesare, Baldi Marzia, Tomatis Stefano, Bifulco Carlo, Santinami Mario
Melanoma Unit, Istituto Nazionale per lo studio e la cura dei Tumori, Via Venezian 1, 20133, Milan, Italy.
Eur J Dermatol. 2002 Nov-Dec;12(6):573-6.
Small pigmented skin lesions represent a new challenge for all physicians devoted to the early diagnosis of melanoma. The purpose of this prospective study was to establish the diagnostic value of the clinical and the dermatoscopic examinations in a population of 157 consecutive patients with 161 small (< or = 6 mm) pigmented lesions, recruited in a short time. Of these 161 lesions, 13 were thin melanomas (median thickness 0.49 mm). In this population, clinical evaluation produced a diagnostic sensitivity of 77% and a specificity of 74%. Dermatoscopy resulted in a sensitivity of 77% and in a specificity of 72%. Combining clinical and dermatoscopic evaluations all the melanomas were preoperatively recognised. The results of the present study stress the complementary role of clinical and dermatoscopic examinations. In particular, clinical evaluation remains of utmost importance in diagnosing melanoma. This concept must be stressed in the education and training of young dermatologists.
对于所有致力于黑色素瘤早期诊断的医生而言,皮肤色素沉着小病灶是一项新的挑战。这项前瞻性研究的目的是,在短时间内招募的157例连续患者、共161处小(≤6mm)色素沉着病灶人群中,确立临床检查和皮肤镜检查的诊断价值。在这161处病灶中,有13处为薄黑色素瘤(中位厚度0.49mm)。在该人群中,临床评估的诊断敏感性为77%,特异性为74%。皮肤镜检查的敏感性为77%,特异性为72%。结合临床和皮肤镜评估,所有黑色素瘤均在术前得到识别。本研究结果强调了临床检查和皮肤镜检查的互补作用。特别是,临床评估在黑色素瘤诊断中仍然至关重要。这一概念在年轻皮肤科医生的教育和培训中必须得到强调。