[烷基化化合物，线粒体ATP合成酶抑制剂]
[Alkylating compounds, inhibitors of mitochondrial ATP-synthetase].
作者信息
Gudz' T I, Iaguzhinskiĭ L S, Skulachev V P
出版信息
Biokhimiia. 1975 Jan-Feb;40(1):89-94.
PMID:124604
Abstract
The esters of aromatic acids with two electrophilic groups were found to inhibit mitochondrial ATP-synthetase like oligomycin. The substances without electrophilic sites or with one electrophilic groups have no the oligomycin-like effect on mitochondria. Aromatic acids with two alkylating groups are also inefficient.
摘要
发现带有两个亲电基团的芳香酸酯能像寡霉素一样抑制线粒体ATP合酶。没有亲电位点或带有一个亲电基团的物质对线粒体没有寡霉素样效应。带有两个烷基化基团的芳香酸也没有效果。
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