Bolca Osman, Hobikoğlu Gültekin, Norgaz Tuğrul, Asiltürk Recep, Unal Sennur, Gürkan Ufuk, Narin Ahmet
Dr.Siyami Ersek Torax and Cardiovascular Surgery Center, Haydarpaşa, Istanbul, Turkey.
Anadolu Kardiyol Derg. 2002 Dec;2(4):302-6.
This study was planned to determine pulmonary artery pressure and pulmonary vascular resistance by using tricuspid annular tissue Doppler imaging in patients with valvular and congenital heart disease.
The study group consisted of patients with valvular and congenital heart disease (n=28). Healthy volunteers (n=10) were included into the control group. Systolic (Sm), early (Em) and late diastolic velocity (Am), isovolumetric relaxation time (IVRTm) were measured from tricuspid annulus by tissue Doppler imaging. Patients of the study group underwent cardiac catheterization and right atrial mean pressure, right ventricle and pulmonary artery systolic- diastolic pressures (PASP and PADP), and pulmonary capillary wedge pressure (PVR, dyn/s/cm-5) were obtained.
There were no significant differences between the groups according to age, gender, left and right ventricle ejection fraction, tricuspid annular Sm, Em and Am velocities and velocity- time integrales (p>0.05). IVRTm was increased in the study group (73.75+/-3.1 ms, p<0.05). For Sm velocities of 11 cm/sec, prediction of PASP >/=30 mmHg was calculated with specificity of 57%, sensitivity of 93%, positive predictive value of 88%, negative predictive value of 68% and accuracy of 75%. For Sm velocities - time integral value of 2.7 cm/sec, prediction of the PVR >/=65 dyn/s/cm-5 was estimated with sensitivity of 88%, specificity of 36%, positive predictive value of 68%, negative predictive value of 66% and accuracy of 68 %.
Pulmonary artery pressure and pulmonary vascular resistance in patients with valvular and congenital heart disease can be predicted by using the Sm wave parameters detected with tricuspid annular tissue Doppler imaging.
本研究旨在通过三尖瓣环组织多普勒成像测定瓣膜性和先天性心脏病患者的肺动脉压和肺血管阻力。
研究组由瓣膜性和先天性心脏病患者(n = 28)组成。健康志愿者(n = 10)纳入对照组。通过组织多普勒成像从三尖瓣环测量收缩期(Sm)、舒张早期(Em)和舒张晚期速度(Am)、等容舒张时间(IVRTm)。研究组患者接受心导管检查,获得右心房平均压、右心室及肺动脉收缩压 - 舒张压(PASP和PADP)以及肺毛细血管楔压(PVR,dyn/s/cm - 5)。
两组在年龄、性别、左、右心室射血分数、三尖瓣环Sm、Em和Am速度及速度 - 时间积分方面无显著差异(p>0.05)。研究组IVRTm增加(73.75±3.1 ms,p<0.05)。对于Sm速度为11 cm/秒,预测PASP≥30 mmHg的特异性为57%,敏感性为93%,阳性预测值为88%,阴性预测值为68%,准确性为75%。对于Sm速度 - 时间积分值为2.7 cm/秒,预测PVR≥65 dyn/s/cm - 5的敏感性为88%,特异性为36%,阳性预测值为68%,阴性预测值为66%,准确性为68%。
通过三尖瓣环组织多普勒成像检测的Sm波参数可预测瓣膜性和先天性心脏病患者的肺动脉压和肺血管阻力。