McGuire J, Wagner F M, Weiss R M
J Urol. 1976 Jan;115(1):53-5. doi: 10.1016/s0022-5347(17)59065-5.
Our 9 patients with severe autonomic dysreflexia treated with phenoxybenzamine, an alpha-sympatholytic agent, had a dramatic relief of symptoms. Bladder and urethral pressure studies before and after treatment with this agent suggest that the inappropriate rise in urethral resistance in these patients is a result of an appropriate but extraordinary response to bladder filling.
我们用α-交感神经阻滞剂酚苄明治疗的9例严重自主神经反射异常患者症状得到显著缓解。使用该药物治疗前后进行的膀胱和尿道压力研究表明,这些患者尿道阻力的不适当升高是对膀胱充盈的适当但异常反应的结果。