Tanaka Jun, Takamoto Satoru, Ryu Tomiko, Ichikawa Kenichiro, Masuo Masatoshi, Saito Toshikazu
Department of Cardiology, Social Insurance General Hospital, Hyakunin-cho 3-22-1, Shinjuku-ku, Tokyo 169-0073.
J Cardiol. 2002 Nov;40(5):225-9.
A 83-year-old woman was admitted because of pretibial edema. Echocardiography demonstrated a huge tumor in the right atrium and ventricle. Transvenous biopsy failed to obtain sufficient specimens for the histological diagnosis. The tumor progressed rapidly and heart failure was intractable. The diagnosis was primary cardiac lymphoma on the basis of elevated soluble interleukin-2 receptor and solitary accumulation of gallium-67 in the heart. Chemotherapy was immediately started. After two courses of chemotherapy, the intracardiac tumor disappeared. However, one month later, the tumor relapsed in the anterior mediastinum. Needle biopsy disclosed diffuse B-cell non-Hodgkin's malignant lymphoma. Additional irradiation reduced the tumor. Early diagnosis and immediate chemotherapy are important for the treatment of primary cardiac lymphoma.
一名83岁女性因胫前水肿入院。超声心动图显示右心房和右心室有一个巨大肿瘤。经静脉活检未能获取足够标本进行组织学诊断。肿瘤进展迅速，心力衰竭难以控制。根据可溶性白细胞介素-2受体升高以及心脏中镓-67的孤立性聚集，诊断为原发性心脏淋巴瘤。立即开始化疗。两个疗程的化疗后，心脏内肿瘤消失。然而，一个月后，肿瘤在前纵隔复发。针吸活检显示为弥漫性B细胞非霍奇金恶性淋巴瘤。额外的放疗使肿瘤缩小。早期诊断和立即化疗对原发性心脏淋巴瘤的治疗很重要。
