Dreyfus Marc, Régnier Philippe
Ecole Normale Supérieure, CNRS UMR8541, 46 rue d'Ulm, 75230, Paris, France.
Cell. 2002 Nov 27;111(5):611-3. doi: 10.1016/s0092-8674(02)01137-6.
In eukaryotes, poly(A) tails usually act as stabilizers of intact mRNAs, whereas in E. coli they serve to accelerate the destruction of fragments. The mechanisms underlying these contrasting effects of the same RNA modification are discussed.
在真核生物中，多聚腺苷酸尾巴通常作为完整信使核糖核酸（mRNA）的稳定剂，而在大肠杆菌中，它们则用于加速片段的降解。本文讨论了相同RNA修饰产生这些相反作用的潜在机制。
