Grewal Raji P
New Jersey Neuroscience Institute, Edison, NJ 08818, USA.
J Clin Neurosci. 2003 Jan;10(1):102-4. doi: 10.1016/s0967-5868(02)00278-3.
A 60 year old right-handed man developed severe amnesia following a left medial temporal stroke as documented by cerebral MRI, MRA and SPECT scans. Neuropsychological evaluation 13 weeks after the stroke showed a profound retrograde amnesia characterised by memory loss for public facts and events over the previous four decades. In addition, autobiographical memory showed selective loss of personal episodic memory with relative preservation of personal semantic memory. The development of this degree of amnesia with these features following a unilateral temporal lobe lesion is unusual. The possible neuroanatomical mechanisms underlying the amnesia and how they relate to current theories of memory loss are discussed.
一名60岁的右利手男性在左侧颞叶内侧中风后出现严重失忆，脑部MRI、MRA和SPECT扫描证实了这一点。中风13周后的神经心理学评估显示出严重的逆行性失忆，其特征是对过去四十年的公共事实和事件记忆丧失。此外，自传体记忆显示个人情景记忆选择性丧失，而个人语义记忆相对保留。单侧颞叶病变后出现这种程度且具有这些特征的失忆并不常见。本文讨论了失忆背后可能的神经解剖学机制以及它们与当前记忆丧失理论的关系。
