Escobar J A, Dover A S, Dueñas A, Leal E, Medina P, Arguello A, de Gaiter M, Greer D L, Spillman R, Reyes M A
Pediatrics. 1976 Jan;57(1):123-30.
One hundred eighty children hospitalized for acute respiratory disease were studied in Cali, Colombia. In the majority of patients, pneumonia was the reason for hospitalization and remained the final diagnosis. Fifty-one cases of pneumonia of indeterminate etiology comprised the largest single diagnostic category, followed by 38 cases of pneumonia associated with measles, and 22 cases assocaited with serologic evidence of infection with other viral agents or Mycoplasma pneumoniae. Etiologic diagnosis could be assigned with a reasonable degree of confidence in 116 of the 180 patients (64%). The laboratory procedure found most likely to provide the etiologic diagnosis in this series was paired sera specimens for demonstration of rise in antibody titer against the common viral respiratory pathogens. Those most frequently implicated serologically as etiologic agents in the cases studied were, in order of decreasing frequency, measles, influenza, parainfluenza, and adenoviruses.
在哥伦比亚的卡利，对180名因急性呼吸道疾病住院的儿童进行了研究。在大多数患者中，肺炎是住院原因且仍是最终诊断结果。51例病因不明的肺炎构成最大的单一诊断类别，其次是38例与麻疹相关的肺炎，以及22例与其他病毒病原体或肺炎支原体感染血清学证据相关的肺炎。在180名患者中的116名（64%）中，可以有合理程度的把握做出病因诊断。在本系列研究中最有可能提供病因诊断的实验室检查是成对血清标本，以证明针对常见病毒性呼吸道病原体的抗体滴度升高。在所研究病例中，血清学上最常被牵连为病原体的依次是（频率从高到低）麻疹、流感、副流感和腺病毒。
