减毒活疫苗免疫后出现的异常自然麻疹。
Exaggerated natural measles following attenuated virus immunization.
作者信息
St Geme J W, George B L, Bush B M
出版信息
Pediatrics. 1976 Jan;57(1):148-9.
PMID:1246490
Abstract
An adolescent girl, devoid of a detectable humoral immunity to measles virus despite two inoculations of live, attenuated vaccine, developed an exaggerated atypical rubeola illness following exposure to wild virus. This observation suggests that attenuated virus may be capable of immunologically sensitizing some individuals as has been described with killed virus vaccine.
摘要
一名青春期女孩尽管接种了两剂减毒活疫苗，但对麻疹病毒仍缺乏可检测到的体液免疫，在接触野生病毒后患上了严重的非典型麻疹。这一观察结果表明，减毒病毒可能像灭活病毒疫苗那样，能够使一些个体产生免疫致敏。
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