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用离子载体X537A处理的非洲爪蟾胚胎眼睛中视网膜的过早特化。

Premature specification of the retina in embryonic Xenopus eyes treated with ionophore X537A.

作者信息

Jacobson M

出版信息

Science. 1976 Jan 23;191(4224):288-90. doi: 10.1126/science.1246612.

DOI:10.1126/science.1246612
PMID:1246612
Abstract

Eyes excised from Xenopus embryos at stages 24 to 25 were cultured for 4 to 6 hours in a medium containing the ionophore X537A or in a control medium. The eyes were implanted either upside down or normally in host embryos at stages 28 to 30, and their retinotectal projections were mapped after metamorphosis. Treatment with X537A prevented realignment of retinal axes in eyes implanted into hosts that were capable of producing retinal axial alignment in all control eyes.

摘要

从处于24至25期的非洲爪蟾胚胎中取出眼睛，在含有离子载体X537A的培养基或对照培养基中培养4至6小时。将眼睛以倒置或正常的方式植入处于28至30期的宿主胚胎中，并在变态后绘制其视网膜-脑顶盖投射图。在所有对照眼中能够使视网膜轴重新排列的宿主中，用X537A处理可阻止植入眼中视网膜轴的重新排列。

相似文献

1
Premature specification of the retina in embryonic Xenopus eyes treated with ionophore X537A.用离子载体X537A处理的非洲爪蟾胚胎眼睛中视网膜的过早特化。
Science. 1976 Jan 23;191(4224):288-90. doi: 10.1126/science.1246612.
2
Visuotectal projections following temporary transplantation of embryonic eyes to the body in Xenopus laevis.
J Embryol Exp Morphol. 1982 Oct;71:97-108.
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Specification of retinotectal connexions during development of the toad Xenopus laevis.非洲爪蟾（ Xenopus laevis）发育过程中视网膜顶盖连接的特异性
J Embryol Exp Morphol. 1980 Feb;55:77-92.
4
Neuronal locus specificity: trans-repolarization of Xenopus embryonic retina after the time of axial specification.神经元位点特异性：非洲爪蟾胚胎视网膜在轴向特化时间之后的跨膜复极化。
Science. 1975 Aug 15;189(4202):563-4. doi: 10.1126/science.1145214.
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Control of pattern duplication in the retinotectal system of Xenopus. Induction of duplication in eye fragments by secondary cuts.非洲爪蟾视网膜顶盖系统中模式复制的控制。通过二次切割诱导眼片段中的复制。
Dev Biol. 1979 Apr;69(2):361-74. doi: 10.1016/0012-1606(79)90297-5.
6
Control of pattern duplication in the retinotectal system of Xenopus. Suppression of duplication by eye-fragment interactions.
Dev Biol. 1979 Apr;69(2):337-60. doi: 10.1016/0012-1606(79)90296-3.
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Specification of positional information in retinal ganglion cells of Xenopus: assays for analysis of the unspecified state.非洲爪蟾视网膜神经节细胞中位置信息的特化：分析未特化状态的检测方法
Proc Natl Acad Sci U S A. 1973 Feb;70(2):507-11. doi: 10.1073/pnas.70.2.507.
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Development of intertectal neuronal connections in xenopus: the effects of contralateral transposition of the eye and of eye removal.非洲爪蟾顶盖间神经元连接的发育：眼的对侧移位和摘除眼的影响。
Exp Brain Res. 1975 Nov 14;23(5):505-18. doi: 10.1007/BF00234918.
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The visuotectal projections made by Xenopus 'pie slice' compound eyes.
J Embryol Exp Morphol. 1983 Apr;74:29-45.
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Stable programming for map orientation in disarranged embryonic eyes in Xenopus.
J Embryol Exp Morphol. 1980 Feb;55:143-65.

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