Whitley T H, Graybill J R, Alford R H
South Med J. 1976 Jan;69(1):33-6. doi: 10.1097/00007611-197601000-00013.
A patient with chronic lymphocytic leukemia developed extensive pneumonia due to Cryptococcus neoformans. A presumptive diagnosis based on results of a Wright's stain of the sputum was made and appropriate antifungal therapy was started. C neoformans was cultured in COUNTS AS HIGH AS 8 X 10(5)/ml of sputum and was present morphologically for three weeks after sputum cultures had become negative. During the patient's first week of hospitalization, C neoformans was cultured from sputum and on cough plates but from no other source in his room. This suggests the possibility of transmitting the fungus to susceptible persons by droplets from patients having extensive pulmonary cryptococcosis.
一名慢性淋巴细胞白血病患者因新型隐球菌感染发生广泛肺炎。根据痰液瑞氏染色结果做出初步诊断，并开始进行适当的抗真菌治疗。新型隐球菌在痰液中的培养计数高达8×10⁵/ml，且在痰液培养转阴后其形态仍持续存在了三周。在患者住院的第一周，从痰液和咳嗽标本中培养出新型隐球菌，但在其病房的其他来源中未培养出。这提示存在通过患有广泛肺部隐球菌病患者的飞沫将真菌传播给易感人群的可能性。
