Rämä P, Sala J B, Gillen J S, Pekar J J, Courtney S M
Johns Hopkins University, 3400 N. Charles Street, Baltimore, MD 21218, USA.
Cogn Affect Behav Neurosci. 2001 Jun;1(2):161-71. doi: 10.3758/cabn.1.2.161.
Working memory for names and faces was investigated to ascertain whether verbal and nonspatial visual information is maintained in working memory by separate neural systems. The subjects performed a delayed match-to-sample task for famous or unfamous faces and names and a sensorimotor control task. Several occipital, temporal, parietal, and prefrontal areas were activated during all memory delays, in comparison with the control delays. Greater delay activity for unfamous faces than for names was obtained in the right fusiform gyrus, right inferior frontal gyrus (IFG), right IFG/precentral gyrus, and right medial superior frontal gyrus, whereas greater delay activity for unfamous names than for faces was observed in the precuneus, left insula/postcentral gyrus, and left IFG/precentral gyrus. There was no significant difference in the prefrontal activity in the comparison between famous faces and names. Greater delay activity for famous names than for faces was obtained in visual association and parietal areas. The results indicate that there is a functional dissociation based on information type within the neural system that is responsible for working memory maintenance of verbal and nonspatial visual information.
研究了对名字和面孔的工作记忆，以确定言语和非空间视觉信息是否由不同的神经系统在工作记忆中维持。受试者对著名或不著名的面孔和名字执行延迟匹配样本任务以及感觉运动控制任务。与对照延迟相比，在所有记忆延迟期间，几个枕叶、颞叶、顶叶和前额叶区域被激活。在右侧梭状回、右侧额下回（IFG）、右侧IFG/中央前回和右侧额上回中部，不著名面孔的延迟活动比名字的延迟活动更大，而在楔前叶、左侧岛叶/中央后回和左侧IFG/中央前回观察到不著名名字的延迟活动比面孔的延迟活动更大。在著名面孔和名字的比较中，前额叶活动没有显著差异。在视觉联合区和顶叶区域，著名名字的延迟活动比面孔的延迟活动更大。结果表明，在负责言语和非空间视觉信息工作记忆维持的神经系统内，基于信息类型存在功能分离。
