Kitaoka Hiroko
Division of Physiologic Imaging, Department of Radiology, University of Iowa College of Medicine, 200 Hawkins Drive, Iowa City, IA 52240, USA.
Eur J Radiol. 2002 Dec;44(3):164-71. doi: 10.1016/s0720-048x(02)00266-8.
The author proposes an entirely new approach called 'virtual imaging' of an organ based on 'computational morphology'. Computational morphology describes mathematically design as principles of an organ structure to generate the organ model via computer, which can be called virtual organ. Virtual imaging simulates image data using the virtual organ. The virtual organ is divided into cubic voxels, and the CT value or other intensity value for each voxel is calculated according to the tissue properties within the voxel. The validity of the model is examined by comparing virtual images with clinical images. Computational image analysis methods can be developed based on validated models. In this paper, computational anatomy of the lung and its virtual X-ray imaging are introduced.
作者提出了一种全新的方法，即基于“计算形态学”对器官进行“虚拟成像”。计算形态学从数学角度将设计描述为器官结构的原理，以便通过计算机生成器官模型，该模型可称为虚拟器官。虚拟成像利用虚拟器官模拟图像数据。虚拟器官被划分为立方像素，每个像素的CT值或其他强度值根据像素内的组织特性进行计算。通过将虚拟图像与临床图像进行比较来检验模型的有效性。基于经过验证的模型可以开发计算图像分析方法。本文介绍了肺的计算解剖学及其虚拟X射线成像。
