Lu Gang, Zhou Gang, Chen Guangyu, Fan Fei, Li Binbin, Wang Lianzhao
Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Beijing 100041, China.
Zhonghua Zheng Xing Wai Ke Za Zhi. 2002 Sep;18(5):280-2.
To investigate the influence of over-expansion on the viability and vascularity of an axial-pattern flap.
Tissue expanders were implanted subcutaneously on the buttock of the mini-pig. After over expansion, an axial-pattern over-expanded skin flap was elevated in the pig of the experimental group. The differences in flap survival, LDF, MDA content and fluorescein stain were observed between the control and the experimental groups. The vascular architecture changes were also recorded using histological and clearing specimen examination.
The microcirculation in the distal segment of the axial flap was significantly weakened after over-expansion. There were injury manifestation, change in vessel distribution and reduction of vascular territory in the axial over-expanded flap.
Over-expansion could cause chronic injuries to the axial vessel network and damage the blood supply of the axial-pattern flap.
探讨过度扩张对轴型皮瓣活力及血管形成的影响。
在小型猪臀部皮下植入组织扩张器。过度扩张后，在实验组猪身上掀起一个轴型过度扩张皮瓣。观察对照组和实验组之间皮瓣存活、激光多普勒血流仪（LDF）、丙二醛（MDA）含量及荧光素染色的差异。还采用组织学和透明标本检查记录血管结构变化。
过度扩张后轴型皮瓣远端段的微循环明显减弱。轴型过度扩张皮瓣存在损伤表现、血管分布改变及血管区域减少。
过度扩张可对轴型血管网造成慢性损伤，损害轴型皮瓣的血供。
