Shanik G D, Ford J, Hayes A C, Baker W H, Barnes R W
Ann Surg. 1976 Feb;183(2):136-8. doi: 10.1097/00000658-197602000-00009.
A prospective randomized trial was undertaken to evaluate effects of lumbar sympathectomy as an adjunct to reconstructive surgery of the lower limb. The objective of this study was to assess the early postoperative effect of these procedures on pedal vasomotor tone. A pedal arterial resistance index (PARI) at rest was derived from the ratio of the ankle-digit systolic pressure gradient and pedal blood flow measured plethysmographically. Studies were performed on 32 normal individuals and pre- and postoperatively in 29 patients undergoing aortic reconstruction, 12 of whom were randomly chosen to have lumbar sympathectomy. The mean postoperative PARI in 17 patients who had reconstructions alone was 42+/-7 (S.E.M.) units which approximated the preoperative PARI (43+/-9 units) and normal control values (45+/-6 units). In contrast, 12 patients who had a concomitant lumbar sympathectomy had a significant reduction in the postoperative PARI (8+/-1 units, Pless than 0.005). These initial results indicate that the addition of lumbar sympathectomy to an aortic reconstruction may enhance blood flow to the foot by significantly reducing outflow resistance.
开展了一项前瞻性随机试验,以评估腰交感神经切除术作为下肢重建手术辅助手段的效果。本研究的目的是评估这些手术对术后早期足部血管舒缩张力的影响。静息状态下的足部动脉阻力指数(PARI)由踝趾收缩压梯度与通过体积描记法测量的足部血流之比得出。对32名正常个体进行了研究,并对29例行主动脉重建术的患者在术前和术后进行了研究,其中12例被随机选择接受腰交感神经切除术。仅接受重建手术的17例患者术后平均PARI为42±7(标准误)单位,接近术前PARI(43±9单位)和正常对照值(45±6单位)。相比之下,12例同时接受腰交感神经切除术的患者术后PARI显著降低(8±1单位,P<0.005)。这些初步结果表明,在主动脉重建术中加用腰交感神经切除术可能通过显著降低流出阻力来增加足部血流。