Canto John G, Zalenski Robert J, Ornato Joseph P, Rogers William J, Kiefe Catarina I, Magid David, Shlipak Michael G, Frederick Paul D, Lambrew Costas G, Littrell Katherine A, Barron Hal V
Chest Pain Center and Division of Cardiovascular Diseases, University of Alabama at Birmingham, 35294-0012, USA.
Circulation. 2002 Dec 10;106(24):3018-23. doi: 10.1161/01.cir.0000041246.20352.03.
National practice guidelines strongly recommend activation of the 9-1-1 Emergency Medical Systems (EMS) by patients with symptoms consistent with an acute myocardial infarction (MI). We examined use of the EMS in the United States and ascertained the factors that may influence its use by patients with acute MI.
From June 1994 to March 1998, the National Registry of Myocardial Infarction 2 enrolled 772 586 patients hospitalized with MI. We excluded those who transferred in, arrived at the hospital >6 hours from symptom onset, or who were in cardiogenic shock. We compared baseline characteristics and initial management for patients who arrived by ambulance versus self-transport. EMS was used in 53.4% of patients with MI, a proportion that did not vary significantly over the 4-year study period. Nonusers of the EMS were on average younger, male, and at relatively lower risk on presentation. In addition, payer status was significantly associated with EMS use. Use of EMS was independently associated with slightly wider use of acute reperfusion therapies and faster time intervals from door to fibrinolytic therapy (12.1 minutes faster, P<0.001) or to urgent PTCA (31.2 minutes faster, P<0.001).
Only half of patients with MI were transported to the hospital by ambulance, and these patients had greater and significantly faster receipt of initial reperfusion therapies. Wider use of EMS by patients with suspected MI may offer considerable opportunity for improvement in public health.
国家实践指南强烈建议,出现与急性心肌梗死(MI)相符症状的患者应激活9-1-1紧急医疗系统(EMS)。我们研究了美国EMS的使用情况,并确定了可能影响急性心肌梗死患者使用EMS的因素。
从1994年6月至1998年3月,心肌梗死国家注册登记2纳入了772586例因心肌梗死住院的患者。我们排除了转院患者、症状发作后6小时以上到达医院的患者或心源性休克患者。我们比较了通过救护车到达与自行前往医院的患者的基线特征和初始治疗情况。53.4%的心肌梗死患者使用了EMS,这一比例在4年的研究期间没有显著变化。未使用EMS的患者平均年龄较小、为男性,就诊时风险相对较低。此外,支付者身份与EMS的使用显著相关。使用EMS与更广泛地使用急性再灌注治疗以及从入院到溶栓治疗(快12.1分钟,P<0.001)或紧急经皮冠状动脉腔内血管成形术(PTCA)(快31.2分钟,P<0.001)的时间间隔更短独立相关。
只有一半的心肌梗死患者通过救护车转运至医院,这些患者能更快且更大量地接受初始再灌注治疗。疑似心肌梗死患者更广泛地使用EMS可能为改善公共卫生提供相当大的机会。