Łebkowski Wojciech J
Klinika Neurochirurgii Akademii Medycznej w Białymstoku.
Pol Merkur Lekarski. 2002 Sep;13(75):188-90.
The aim of study was to evaluate the degree of lumbar intervertebral disc degeneration during post-mortem studies, and its relation to the age and gender of cadavers. The changes of intervertebral disc were classified according to Nachemson [13]. The study included 308 lumbar intervertebral discs taken during autopsy from 57 females (mean age 41.83) and 79 males (mean age 42.06). Two hundred and forty discs showed degenerative changes. The statistic analysis revealed that the degeneration is more pronounced with age (ANOVA p < 0.05). The study demonstrated that in males degeneration occurs a decade earlier than in females, and could be observed in the second decade of life. Similarly, the degeneration of 3rd or 4th grade could be observed a decade earlier in men than in women. The statistical analysis revealed the differences (p < 0.05) in degeneration between upper (levels L2 and L3), and lower (levels L4 and L5) lumbar spine. Analysing the discs as single levels, no statistical differences in degeneration were observed.
本研究的目的是在尸检研究中评估腰椎间盘退变的程度，以及其与尸体年龄和性别的关系。椎间盘的变化根据纳赫姆森[13]进行分类。该研究包括从57名女性（平均年龄41.83岁）和79名男性（平均年龄42.06岁）尸检中获取的308个腰椎间盘。240个椎间盘显示出退变变化。统计分析表明，退变随年龄增长更为明显（方差分析p<0.05）。该研究表明，男性退变比女性早十年出现，且在生命第二个十年即可观察到。同样，男性三级或四级退变比女性早十年出现。统计分析显示，腰椎上部（L2和L3节段）和下部（L4和L5节段）之间的退变存在差异（p<0.05）。将椎间盘作为单个节段分析时，未观察到退变存在统计学差异。
