Reingardiene Dagmara
Kauno medicinos universiteto Intensyviosios terapijos klinika, Eiveniu 2, 3007 Kaunas.
Medicina (Kaunas). 2002;38(5):573-81; quiz 582.
Over the past three decades, the significant morbidity and mortality associated with candidemia and invasive candidiasis have been well established. Technological and scientific advancement had led to an increase in the incidence of serious Candida infections. With the introduction of the azoles and other antifungal agents, our ability to treat these infections has improved; however, our ability to diagnose these infections in a timely fashion remains limited, and patient outcomes remain poor. This review article discusses these problems, the role of antifungal prophylaxis, risk factors for invasive Candida infection and treatment of systemic Candida infection.
在过去三十年中，念珠菌血症和侵袭性念珠菌病所带来的显著发病率和死亡率已得到充分证实。技术和科学的进步导致严重念珠菌感染的发病率有所上升。随着唑类药物和其他抗真菌药物的引入，我们治疗这些感染的能力有所提高；然而，我们及时诊断这些感染的能力仍然有限，患者的治疗效果也依然不佳。这篇综述文章讨论了这些问题、抗真菌预防的作用、侵袭性念珠菌感染的危险因素以及全身性念珠菌感染的治疗。
