Strategy for the resolution of a chiral dearomatization agent:[TpRe(CO)(1-methylimidazole)] coordination of alpha-pinene (Tp = hydridotris(pyrazolyl)borate).
作者信息
Meiere Scott H, Valahovic Mark T, Harman W Dean
机构信息
Department of Chemistry, University of Virginia, Charlottesville, VA 22901, USA.
出版信息
J Am Chem Soc. 2002 Dec 18;124(50):15099-103. doi: 10.1021/ja0118845.
PMID:12475356
Abstract
A methodology for resolving TpRe(CO)(1-methylimidazole)(eta(2)-benzene) has been developed utilizing (R)-alpha-pinene. Each enantiomer of the [TpRe(CO)(MeIm)] system can be obtained with the enantiomer ratio (er) = 97:3 by taking advantage of differing rates of pinene substitution for the two diastereomers of TpRe(CO)(MeIm)(eta(2)-(R)-alpha-pinene).
摘要
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