Lemieux Julie, Bernier Vincent, Martel Nadine, Delage Robert
Centre d'Hématologie et d'Immunologie Clinique, Hôpital du St-Sacrement, Université Laval, 1050 Chemin Ste-Foy, Quebec, Que, Canada G1S 4L8.
Hematology. 2002 Dec;7(6):355-8. doi: 10.1080/1024533021000053407.
Lymphomatoid granulomatosis (LG) is a rare lymphoproliferative disorder. There is no standard therapy for refractory patient. Here we present the case of a patient with LG of the lung and the brain who was refractory to polychemotherapy. An autologous hematopoietic stem cell transplantation was done and the patient achieved a complete remission. This represents the first case of high-dose chemotherapy with hematopoietic stem cell support in this disease.
淋巴瘤样肉芽肿病(LG)是一种罕见的淋巴增殖性疾病。对于难治性患者尚无标准治疗方法。在此,我们报告一例肺部和脑部患LG且对多药化疗难治的患者。该患者接受了自体造血干细胞移植并实现了完全缓解。这是该疾病中首例采用造血干细胞支持的大剂量化疗病例。