Jansson Sven-Arne, Andersson Fredrik, Borg Sixten, Ericsson Asa, Jönsson Elsy, Lundbäck Bo
OLIN Studies, Department of Medicine, Sunderby Central Hospital of Norrbotten, Luleå, Sweden.
Chest. 2002 Dec;122(6):1994-2002. doi: 10.1378/chest.122.6.1994.
COPD is a common and disabling disease that entails high costs for society. The objectives of this study were to measure the societal costs of COPD in Sweden, and to examine the relationship between severity of illness and costs.
The costs of COPD were examined using a well-defined and representative cohort of subjects with mild, moderate, and severe COPD. Regular telephone interviews regarding resource utilization were made to a cohort of 212 subjects with COPD derived from studies of the general population in Northern Sweden.
The annual per capita cost for COPD in Swedish crowns (SEK) was estimated at SEK 13,418 (1,284 US dollars (USD); 1,448 euros (EUR). The direct and indirect costs were SEK 5,592 (42%) and SEK 7,828 (58%), respectively. A highly significant relationship was found between severity of disease and costs. Costs for severe disease were 3 times as high as costs for moderate disease and > 10 times as high as for mild disease. Large individual variations in the level of costs were found.
Assuming that the prevalence and treatment patterns are representative of Sweden as a whole, the total costs of COPD to society in 1999 were estimated at SEK 9.1 billion (USD 871 million; EUR 982 million). Subjects with mild disease (83%) accounted for 29%, while subjects with moderate disease (13%) accounted for 41% of the total costs. The subjects with severe disease (4%) accounted for the remainder (30%). Prevention, early diagnosis, and postponement of disease progression should have large monetary and policy implications.
慢性阻塞性肺疾病（COPD）是一种常见且使人丧失劳动能力的疾病，给社会带来高昂成本。本研究的目的是衡量瑞典COPD的社会成本，并考察疾病严重程度与成本之间的关系。
使用一组定义明确且具有代表性的轻度、中度和重度COPD患者来研究COPD的成本。对来自瑞典北部普通人群研究的212例COPD患者进行定期电话访谈，了解资源利用情况。
COPD的人均年成本估计为13418瑞典克朗（SEK）（1284美元（USD）；1448欧元（EUR））。直接成本和间接成本分别为5592瑞典克朗（42%）和7828瑞典克朗（58%）。发现疾病严重程度与成本之间存在高度显著的关系。重度疾病的成本是中度疾病成本的3倍，是轻度疾病成本的10倍以上。成本水平存在较大的个体差异。
假设患病率和治疗模式能代表整个瑞典，1999年COPD给社会造成的总成本估计为91亿瑞典克朗（8.71亿美元；9.82亿欧元）。轻度疾病患者（83%）占总成本的29%，而中度疾病患者（13%）占总成本的41%。重度疾病患者（4%）占其余部分（30%）。预防、早期诊断和延缓疾病进展应具有重大的经济和政策意义。
