Mydlil V, Tomasová H, Cápová E, Cerná M
Biol Neonate. 1976;28(1-2):36-41. doi: 10.1159/000240802.
The authors measured erythrocyte acetylcholinesterase (ACHE) activity in 51 physiologic newborn infants, 35 pregnant women and 101 infants with hyperbilirubinemia caused by hemolytic diseases in the ABO and Rh systems, or of other origin (6 children). In total, 374 examinations of erythrocyte ACHE were performed. The normal values of physiologic infants during the first hours of life were 0.162 +/- 0.03, at the age of 3 days 0.104 +/- 0.04. The values in pregnant women were 0.206 +/- 0.07. The ACHE activity was considerably decreased in newborn infants affected by erythroblastosis-ABO, and its mean value, in the case of exsanguinotransfusion indicated by the Polácek scheme, amounted to 0.060 +/- 0.051. It raised after exsanguinotransfusion and was equal to the value of red cells transfused. In newborn infants affected by erythroblastosis-Rh, the value decreased in the cases complicated with asphyxia. Low values of ACHE are sometimes found in certain cases of IRDS or of septicemia. The determination of erythrocyte ACHE activity enables assessing the state of red blood cells.
作者测定了51名生理性新生儿、35名孕妇以及101名因ABO和Rh系统溶血性疾病或其他原因（6名儿童）导致高胆红素血症的婴儿的红细胞乙酰胆碱酯酶（ACHE）活性。总共进行了374次红细胞ACHE检测。生理性婴儿出生后最初几小时的正常值为0.162±0.03，3天时为0.104±0.04。孕妇的值为0.206±0.07。患有ABO血型不合溶血病的新生儿的ACHE活性显著降低，按照波拉切克方案进行换血输血时，其平均值为0.060±0.051。换血输血后该值升高，且与所输红细胞的值相等。患有Rh血型不合溶血病的新生儿，在并发窒息的情况下该值降低。在某些呼吸窘迫综合征或败血症病例中有时会发现ACHE值较低。测定红细胞ACHE活性有助于评估红细胞的状态。
