Tamura M, Ohta Y, Ishikawa N, Tsunezuka Y, Oda M, Watanabe G
First Department of Surgery, School of Medicine, Kanazawa University, Kanazawa, Japan.
Kyobu Geka. 2002 Dec;55(13):1105-9.
Nine cases of thymic carcinoma (mean age 53.9 years old, 8 males and 1 female) were treated in our hospital from 1973 to 1998. The histological subtypes of thymic carcinoma were squamous cell in six, adenosquamous cell in one, Lymphoepithelioma-like carcinoma in one, mixed type of small cell and squamous cell in one. We applied Yamakawa clinical staging, 9 cases consisted of 2 stage II cases, 2 stage III cases, and 5 stage IV b cases. Adjuvant radiotheraphy was administered in one case, registering remarkable reduction of tumor size. All of the four cases which had been performed complete resection are alive without recurrence for 17 to 136 months after operation. The mean survival time was 47 months in stage III, and 18 months in stage IV b. By the review of the Japanese literature, most of the patient who revealed long-term survival fulfill the conditions as follow, squamous cell carcinoma in histologically, earlier stage than III at his operation, performed complete resection, performed postoperative radiotherapy. Our cases covering all these condition are alive without carcinoma for 136 months after operation.
1973年至1998年期间，我院共收治9例胸腺癌患者（平均年龄53.9岁，8例男性，1例女性）。胸腺癌的组织学亚型包括鳞状细胞癌6例、腺鳞癌1例、淋巴上皮瘤样癌1例、小细胞和鳞状细胞混合型1例。我们采用山川临床分期，9例患者中包括2例II期、2例III期和5例IVb期。1例患者接受了辅助放疗，肿瘤大小显著缩小。所有4例行根治性切除的患者术后17至136个月均存活且无复发。III期患者的平均生存时间为47个月，IVb期为18个月。通过查阅日本文献，大多数长期存活的患者符合以下条件：组织学类型为鳞状细胞癌、手术时处于III期之前的早期阶段、行根治性切除、术后行放疗。我们的病例满足所有这些条件，术后136个月无癌存活。
