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[一例在服用咪唑立宾期间发生的伴有显著高尿酸血症的急性肾衰竭病例]

[A case of acute renal failure with marked hyperuricemia developing during mizoribine administration].

作者信息

Kushihata Shigeyuki, Hirabayashi Akira, Sekiguchi Yoshitaka, Nagai Kenichi, Arata Toshihiko

机构信息

JA Hiroshima General Hospital, Japan.

出版信息

Nihon Jinzo Gakkai Shi. 2002 Oct;44(7):543-6.

Abstract

A 50-year-old man diagnosed as having AGA(Churg-Strauss syndrome) was administered steroid. After treatment with mizoribine, hyperuricemia and acute renal failure occurred as side effects of this drug. Accordingly we started dialysis treatment, terminated mizoribine treatment, and administered allopurinol dosage. Hemodialysis was necessary every day for 11 days and his renal function recovered after one month. In 67Ga scintigraphy, accumulation of 67Ga was seen in the kidney.

摘要

一名50岁被诊断患有变应性肉芽肿性血管炎(Churg-Strauss综合征)的男性接受了类固醇治疗。在使用咪唑立宾治疗后,出现了高尿酸血症和急性肾衰竭等该药物的副作用。因此,我们开始了透析治疗,停止了咪唑立宾治疗,并给予别嘌醇剂量。连续11天每天都需要进行血液透析,1个月后他的肾功能恢复。在67Ga闪烁扫描中,在肾脏中可见67Ga的积聚。

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