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生殖中的甲状腺问题。

Thyroid issues in reproduction.

作者信息

Johnson Cheri A

机构信息

Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, E. Lansing, MI 48824-1314, USA.

出版信息

Clin Tech Small Anim Pract. 2002 Aug;17(3):129-32. doi: 10.1053/svms.2002.34643.

Abstract

Observations in people and animals demonstrate relationships between thyroid and reproductive functions. Thyroid issues of importance to small animal reproduction are twofold. First, some thyroid disorders, such as lymphocytic thyroiditis and some forms of congenital hypothyroidism, appear to be heritable. Those traits might be considered undesirable. If so, to eliminate the trait affected animals would not be selected as breeding stock. Second, thyroid disorders may adversely affect fertility, pregnancy, or neonatal health. If a causal relationship existed between thyroid and reproductive disorders, correction of one would be expected to result in resolution of the other. This is often not the case. Although animals and people with thyroid disorders may also have reproductive disorders, usually disorders other than thyroid disease are the cause of reproductive abnormalities. It appears that euthyroidism supports optimal reproductive performance, but clinically significant reproductive dysfunction is manifested only under certain uncommon conditions of thyroid disease in dogs and cats.

摘要

对人和动物的观察表明甲状腺与生殖功能之间存在关联。对小动物繁殖具有重要意义的甲状腺问题有两个方面。首先,一些甲状腺疾病,如淋巴细胞性甲状腺炎和某些形式的先天性甲状腺功能减退,似乎具有遗传性。这些特征可能被认为是不理想的。如果是这样,为了消除该特征,受影响的动物将不会被选作种畜。其次,甲状腺疾病可能会对生育能力、妊娠或新生儿健康产生不利影响。如果甲状腺与生殖疾病之间存在因果关系,那么纠正其中一个有望导致另一个问题的解决。但情况往往并非如此。虽然患有甲状腺疾病的动物和人也可能患有生殖疾病,但通常甲状腺疾病以外的其他疾病才是生殖异常的原因。似乎甲状腺功能正常有助于实现最佳生殖性能,但临床上显著的生殖功能障碍仅在犬猫甲状腺疾病的某些不常见情况下才会表现出来。

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