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一项关于接受人工尿道括约肌治疗根治性前列腺切除术后尿失禁男性的泌尿及健康相关生活质量结局的全国性调查。

A national survey of urinary and health related quality of life outcomes in men with an artificial urinary sphincter for post-radical prostatectomy incontinence.

作者信息

Dalkin Bruce L, Wessells Hunter, Cui Haiyan

机构信息

Section of Urology, Department of Biostatistics, University of Arizona, Tucson, AZ, USA.

出版信息

J Urol. 2003 Jan;169(1):237-9. doi: 10.1016/S0022-5347(05)64076-1.

DOI:10.1016/S0022-5347(05)64076-1
PMID:12478144
Abstract

PURPOSE

We determine health related quality of life and urinary outcomes of men undergoing implantation of an artificial urinary sphincter for post-radical prostatectomy incontinence.

MATERIALS AND METHODS

Through a data base provided by American Medical Systems, we mailed the UCLA Prostate Cancer Index to men who underwent artificial urinary sphincter implantation during 6-month intervals in 1995 in 1999, providing 5 and 2-year followup data, respectively.

RESULTS

Of the anonymous questionnaires 36% were returned from the 1995 cohort and 45% from the 1999 cohort. Age adjusted mean scores for the 8 health related quality of life domains were comparable in both groups. Urinary function and bother scores were worse in the 1995 cohort compared to the 1999 group (40 and 48 versus 53 and 58, respectively, p <0.001), with pad use of 97% and 83% respectively. Revision rates were 16% at 2 years and 28% at 5 years after implantation.

CONCLUSIONS

Our national survey revealed that despite significant differences in urinary function and bother, men 2 and 5 years after artificial urinary sphincter implantation had similar general health related quality of life. The continence outcomes differed from most single institution studies in that men after sphincter implantation reported a high degree of urinary dysfunction and bother. Artificial urinary sphincter implantation may significantly improve scores in urinary function but continued pad use is to be expected.

摘要

目的

我们确定接受人工尿道括约肌植入术以治疗根治性前列腺切除术后尿失禁的男性的健康相关生活质量和排尿结果。

材料与方法

通过美国医疗系统公司提供的数据库,我们将加州大学洛杉矶分校前列腺癌指数邮寄给在1995年至1999年期间每隔6个月接受人工尿道括约肌植入术的男性,分别提供5年和2年的随访数据。

结果

1995年队列中有36%的匿名问卷被返回,1999年队列中有45%的问卷被返回。两组在8个健康相关生活质量领域的年龄调整后平均得分相当。1995年队列的排尿功能和困扰得分比1999年组更差(分别为40和48,而1999年组为53和58,p<0.001),使用尿垫的比例分别为97%和83%。植入术后2年的翻修率为16%,5年为28%。

结论

我们的全国性调查显示,尽管排尿功能和困扰存在显著差异,但人工尿道括约肌植入术后2年和5年的男性在一般健康相关生活质量方面相似。控尿结果与大多数单机构研究不同,因为括约肌植入术后的男性报告了高度的排尿功能障碍和困扰。人工尿道括约肌植入术可能会显著提高排尿功能评分,但预计仍会继续使用尿垫。

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