Dahanukar Vilas H, Zavialov Ilia A
Schering-Plough Research Institute, Department of Synthetic Chemistry, 1011 Morris Avenue, Mailstop U-3-2-2100, Union, NJ 07083, USA.
Curr Opin Drug Discov Devel. 2002 Nov;5(6):918-27.
Recent methods for the synthesis of aziridines and aziridinium ions, the mechanisms of their nucleophilic ring-opening reactions and applications to the practical synthesis of pharmaceutical intermediates are reviewed.
综述了近期氮杂环丙烷和氮杂环丙鎓离子的合成方法、亲核开环反应机理及其在药物中间体实际合成中的应用。
