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[双侧原发性肾上腺淋巴瘤:一种不寻常的表现]

[Bilateral primary adrenal lymphoma: an unusual presentation].

作者信息

Alama Zaragoza M A, Robles Iniesta A, Roca Adelantado I, Sales Maicas M A, Navarro de León M C, Román Sánchez P

机构信息

Servicios de Medicina Interna, Hospital de Requena, SVS, Requena, Valencia.

出版信息

An Med Interna. 2002 Oct;19(10):524-6.

Abstract

A case of primary adrenal bilateral non-Hodgking lymphoma, with depressed adrenal reserve is presented. This rare neoplasm causes rapid evolution and fatal outcome in most cases. In our patient, lethal outcome was associated with severe hypercalcemia and refractary hypotension. Many other complications are due to tumoral lysis syndrome associated with high steroid doses in adrenal insufficiency. This rare entity must be included in the differencial diagnosis of adrenal masses, uni or bilateral, because early diagnostic is important for preventing complications, potentially lethals and for improving survival. Image thecnics and ultrasound-guided or computed-tomography-guided FNA, are best diagnostic methods, but in many cases, definitive diagnostic is obtained by necropsy.

摘要

本文报告一例原发性双侧肾上腺非霍奇金淋巴瘤伴肾上腺储备功能减退的病例。这种罕见的肿瘤在大多数情况下会导致病情迅速进展并致命。在我们的患者中,致命结局与严重高钙血症和难治性低血压有关。许多其他并发症是由于肾上腺功能不全时高剂量类固醇导致的肿瘤溶解综合征所致。这种罕见的疾病必须纳入肾上腺肿块(单侧或双侧)的鉴别诊断中,因为早期诊断对于预防潜在致命的并发症和提高生存率很重要。影像学技术以及超声引导或计算机断层扫描引导下的细针穿刺抽吸活检是最佳诊断方法,但在许多情况下,最终诊断是通过尸检获得的。

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