Ozimek Alexandra, Diebold J, Linke R, Heyn J, Hallfeldt K K J, Mussack T
Department of Surgery Innenstadt, Klinikum der Universität München, München, Germany.
Eur J Med Res. 2008 May 26;13(5):221-8.
Primary adrenal non-Hodgkin's lymphoma (PAL) is a rare neoplastic disease. Clinical symptoms are often related to the presence of lymphoma or adrenal insufficieny. Diagnostic strategies include endocrine evaluation, imaging studies and histopathological examination. In case of suspicious PAL, percutaneous CT or US-guided needle biopsy is recommended to rapidly establish diagnosis before starting chemotherapy. We report about an 84-year-old male who presented with significant weight loss and chronic lumbar pain. Abdominal CT scans revealed bilateral masses highly suggestive of malignancy. After open bilateral adrenalectomy with abdominal lymphadenectomy, histological examination showed bilateral PAL. Five months after surgery, the patient died due to progressive tumor disease.
原发性肾上腺非霍奇金淋巴瘤(PAL)是一种罕见的肿瘤性疾病。临床症状通常与淋巴瘤的存在或肾上腺功能不全有关。诊断策略包括内分泌评估、影像学检查和组织病理学检查。对于疑似PAL的病例,建议在开始化疗前进行经皮CT或超声引导下针吸活检以迅速确诊。我们报告了一名84岁男性,他出现显著体重减轻和慢性腰痛。腹部CT扫描显示双侧肿块,高度提示为恶性肿瘤。在进行开放性双侧肾上腺切除术及腹部淋巴结清扫术后,组织学检查显示为双侧PAL。术后五个月,患者因肿瘤进展而死亡。