Arslan Hüseyin, Subaşý Mehmet, Kesemenli Cumhur, Ersuz Hüseyin
Department of Orthopedic and Trauma Surgery, University of Dicle School of Medicine, 21280 Diyarbakýr, Turkey.
Arch Orthop Trauma Surg. 2002 Dec;122(9-10):494-8. doi: 10.1007/s00402-002-0439-y. Epub 2002 Oct 24.
Because of favorable local biological factors, nonunion is rarely seen in long bone fractures in children, and there are few studies on pediatric nonunion in the literature.
Twenty-six children under 15 years of age diagnosed with long bone nonunion were examined, and 19 received treatment. Patients with pseudarthrosis due to tumors or congenital causes were excluded from the study. The following factors were assessed for each patient: age and sex; cause, location, and type of fracture; form of initial treatment; incidence of infection and type of bacteria produced; time between fracture and diagnosis; and type of nonunion.
Twenty-two of the patients had fractures in the lower extremities, and 4 in the upper extremities. The femur was the most commonly affected bone (12 patients), followed by the tibia (10 patients). The average age of the patients was 9.6 years (range 1-15 years). The frequency of occurrence increased after the age of 6, and all patients but two were above this cutoff age. In each case, there was at least one factor contributing to nonunion, such as open reduction and insufficient fixation, open fracture, and infection. Of the 19 patients treated, 3 required reoperation.
In our opinion, claims that pediatric nonunion is an extremely rare condition are exaggerated, and we do not agree that it is always due to an error in treatment. Nonunion does occur in children despite appropriate treatment, especially after the age of 6, and it may be resistant to therapy.
由于局部生物学因素有利,儿童长骨骨折很少发生骨不连,且文献中关于儿童骨不连的研究较少。
对26例15岁以下诊断为长骨骨不连的儿童进行检查,其中19例接受了治疗。因肿瘤或先天性原因导致假关节的患者被排除在研究之外。对每位患者评估以下因素:年龄和性别;骨折的原因、部位和类型;初始治疗方式;感染发生率及产生的细菌类型;骨折与诊断之间的时间;以及骨不连的类型。
22例患者下肢骨折,4例上肢骨折。股骨是最常受累的骨骼(12例患者),其次是胫骨(10例患者)。患者的平均年龄为9.6岁(范围1 - 15岁)。6岁以后发生率增加,除两名患者外所有患者均高于此临界年龄。在每种情况下,至少有一个导致骨不连的因素,如切开复位及固定不充分、开放性骨折和感染。在接受治疗的19例患者中,3例需要再次手术。
我们认为,声称儿童骨不连极为罕见的说法有些夸张,而且我们不同意它总是由治疗失误导致。尽管进行了适当治疗,骨不连在儿童中确实会发生,尤其是6岁以后,并且可能对治疗有抵抗性。