人类数量性状基因座的连锁图谱：概述

Linkage mapping of quantitative trait loci in humans: an overview.

作者信息

Ghosh S, Reich T, Majumder P P

机构信息

Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110-1093, USA.

出版信息

Ann Hum Genet. 2002 Nov;66(Pt 5-6):431-8. doi: 10.1017/S0003480002001240.

DOI:10.1017/S0003480002001240

PMID:12485475

Abstract

In this article, we provide an overview of the different statistical procedures that have been developed for linkage mapping of quantitative trait loci. We outline the model assumptions, the data requirements and the underlying tests for linkage for the different methods.

摘要

在本文中，我们概述了为数量性状基因座连锁图谱构建而开发的不同统计程序。我们概述了不同方法的模型假设、数据要求以及连锁的基础检验。