Desai Bhushan V, Reiter Harvard, Morrison Donald A
Laboratory for Molecular Biology, Department of Biological Sciences, University of Illinois at Chicago, 900 S Ashland Avenue, Chicago, IL 60607, USA.
J Bacteriol. 2003 Jan;185(1):371-3. doi: 10.1128/JB.185.1.371-373.2003.
Mutant strains of Streptococcus pneumoniae were constructed to monitor the regulation of three dispersed genes known or predicted to act in choline metabolism. One gene (licD2) was regulated in response to choline deprivation over a 30-fold range. The other two (SP1860 and licC) responded little if at all to the same challenge.
构建了肺炎链球菌突变株,以监测已知或预测在胆碱代谢中起作用的三个分散基因的调控情况。一个基因(licD2)在胆碱缺乏的情况下,表达量在30倍范围内受到调控。另外两个基因(SP1860和licC)对同样的刺激几乎没有反应。