Michna G, Ghanem N, Laubenberger J, Schneider B, Kromeier J, Langer M
Radiologisches Institut,Klinikum Offenburg.
Radiologe. 2002 Dec;42(12):993-9. doi: 10.1007/s00117-002-0825-z.
Lymph node histology and staging with cross sectional imaging remains basis for the treatment planning in primary malignant lymphoma. Contrast enhanced computed tomography is considered to be gold standard. However, MRI is equally able to provide staging and follow up in the same quality as helical CT, as several studies and clinical experience show. MRI is considered as the superior imaging modality for extranodal lymphoma. Advantages of MRI are that it works without ionizing radiation and contrast media;however, MRI is more expensive and time consuming. However, both imaging modalities are limited by the fact that the differentiation of affected and non affected lymph nodes is based on size only. Also the results of recent clinical studies with USPIOs (SINEREM((R):)) for intravenous MR lymphography in primary malignant lymphoma do not look promising. Despite these disadvantages of MRI, for young patients with malignant lymphoma radiation protection should be taken into account because of frequent imaging in staging and follow up.
淋巴结组织学检查及结合横断面成像进行分期仍是原发性恶性淋巴瘤治疗方案制定的基础。增强计算机断层扫描被视为金标准。然而，正如多项研究及临床经验所示，磁共振成像（MRI）同样能够提供与螺旋CT质量相当的分期及随访结果。MRI被认为是结外淋巴瘤的 superior 成像方式。MRI的优势在于其无需电离辐射及造影剂即可工作；然而，MRI成本更高且耗时更长。不过，这两种成像方式都存在局限性，即区分受影响和未受影响的淋巴结仅基于大小。近期关于超顺磁性氧化铁（USPIOs）（SINEREM((R))）用于原发性恶性淋巴瘤静脉磁共振淋巴造影的临床研究结果也不太乐观。尽管MRI存在这些缺点，但对于患有恶性淋巴瘤的年轻患者，由于在分期及随访中需要频繁成像，应考虑辐射防护。
