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居住在结核病/艾滋病毒高流行区的2例艾滋病患者中的支气管肺卡波西肉瘤病

[Bronchopulmonary Kaposi's disease in 2 AIDS patients living in a zone of high tuberculosis/HIV prevalence].

作者信息

Ouedraogo M, Ouedraogo S M, Zoubga Z A, Badoum G, Ouedraogo G, Boncoungou K, Drabo Y J

机构信息

Service de Pneumologie, Centre Hospitalier National Yalgado-Ouedraogo (CHNYO), Ouagadougou, Burkina-Faso.

出版信息

Rev Pneumol Clin. 2002 Jun;58(3 Pt 1):163-7.

Abstract

The epidemic form of Kaposi's disease, called Kaposi-AIDS, was first described in 1981 by Hymmes in two young AIDS patients. Lung lesions are observed in 10 to 45% of patients with cutaneous Kaposi and are the second leading localization of visceral involvement after the digestive tract. Diagnosis and management of these visceral forms remains difficult. We report two cases of broncho-pulmonary Kaposi-AIDS in two patients treated for cutaneous Kaposi's disease. The diagnosis was made on the basis of epidemiological, clinical, biological, radiological, endoscopic, and histological evidence. The diagnosis was achieved by elimination after ruling out all other opportunistic diseases with pulmonary tropism. The fear of miliary tuberculosis remains strong in zones with a high prevalence of tuberculosis. Despite considerable improvement with antiretroviral drugs, especially antiproteases, outcome remains unpredictable with or without specific treatment.

摘要

卡波西氏病的流行形式,即所谓的卡波西-艾滋病,于1981年由海姆斯首次在两名年轻的艾滋病患者中描述。在10%至45%的皮肤型卡波西氏病患者中可观察到肺部病变,肺部是继消化道之后第二个主要的内脏受累部位。这些内脏型卡波西氏病的诊断和管理仍然困难。我们报告了两名接受皮肤型卡波西氏病治疗的患者发生支气管-肺卡波西-艾滋病的病例。诊断基于流行病学、临床、生物学、放射学、内镜和组织学证据。在排除所有其他具有肺嗜性的机会性疾病后,通过排除法做出诊断。在结核病高流行地区,对粟粒性肺结核的担忧仍然很大。尽管抗逆转录病毒药物,尤其是抗蛋白酶药物取得了显著进展,但无论是否进行特异性治疗,预后仍然不可预测。

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