Hashizume Toshihiko
Department of Internal Medicine, Yokohama Sakaekyosai Hospital, Yokohama, Kanagawa.
Intern Med. 2002 Nov;41(11):1062-4. doi: 10.2169/internalmedicine.41.1062.
In a rare case of Good's syndrome with pernicious anemia, one year after thymectomy, recurrent respiratory infections developed. Both panhypoglobulinemia and pernicious anemia were disclosed. An immunological analysis revealed the absence of circulating B cells, but T cell numbers and mitogenic responses were normal. Regular gammaglobulin and vitamin B12 injections were successful in keeping the patient symptom free.
在一例罕见的伴有恶性贫血的古德综合征病例中,胸腺切除术后一年出现反复呼吸道感染。同时发现全血细胞减少和恶性贫血。免疫分析显示循环B细胞缺失,但T细胞数量和有丝分裂反应正常。定期注射丙种球蛋白和维生素B12成功地使患者保持无症状状态。