Takami H, Sasaki Y, Ikeda Y, Tajima G
Department of Surgery, Teikyo University School of Medicine, 2-11-1, Kaga, Itabashi-ku, Tokyo 173-8605, Japan.
Biomed Pharmacother. 2002;56 Suppl 1:26s-30s. doi: 10.1016/s0753-3322(02)00260-3.
Intraoperative quick parathyroid hormone (QPTH) assay is claimed to prevent failure during parathyroidectomy for hyperparathyroidism. The causes of operative failure have included multiglandular disease, ectopic parathyroid glands, supernumerary parathyroid glands, errors in frozen section evaluations, and missed diagnosis. A QPTH assay has been recognized as a useful method of determining whether hyperfunctioning tissues have been completely excised. However, an intraoperative QPTH assay may fail to detect the presence of double parathyroid adenomas. Use of this assay in conjunction with preoperative and intraoperative localization studies has led to the advocacy of more directed cervical procedures, such as limited, video-assisted, and endoscopic parathyroidectomy.
术中快速甲状旁腺激素（QPTH）检测据称可预防甲状旁腺功能亢进症甲状旁腺切除术中的失败情况。手术失败的原因包括多腺体疾病、异位甲状旁腺、甲状旁腺增生、冰冻切片评估错误以及漏诊。QPTH检测已被公认为确定功能亢进组织是否已被完全切除的有用方法。然而，术中QPTH检测可能无法检测到双发性甲状旁腺腺瘤的存在。将该检测与术前和术中定位研究相结合，促使人们提倡采用更具针对性的颈部手术，如有限的、视频辅助的和内镜下甲状旁腺切除术。
